The majority of aberrations are sporadic although on rare occasions a chromosomal disorder is directly inherited. 尽管偶尔可见一种染色体疾病是直接遗传的，但是大量的染色体异常是散发的。
A number of investigators have suggested that chromosomal anomalies can contribute to human infertility causing spermatogenetic derangement. 一些调查表明，染色体异常可导致生精紊乱而造成人类不孕不育。
